After the birth of Barrymore’s daughters, the actress intended to leave on-screen work behind. It wasn’t until after her 2016 divorce that she was approached with the opportunity to appear in Santa Clarita Diet. Barrymore says that she was initially hesitant to accept the offer—but she ended up taking the job regardless, and now says that it awakened her.
Santa Clarita Diet is an American horror-comedy web television series created by Victor Fresco for the streaming service Netflix, starring Drew Barrymore and Timothy Olyphant. Fresco serves as the showrunner, and is an executive producer alongside Drew Barrymore, Timothy Olyphant, Aaron Kaplan, Tracy Katsky, Chris Miller, Ember Truesdell and Ruben Fleischer.